About   Help   FAQ
Symbol
Name
ID 		Lbr
lamin B receptor
MGI:2138281
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgM level
Bone marrow hypocellularity
Abnormal leukocyte morphology
Neutropenia
Abnormality of neutrophils
Hyposegmentation of neutrophil nuclei
Thrombocytopenia
Giant platelets
Splenomegaly
Hepatosplenomegaly
Disease(s) Associated with LBR
Greenberg dysplasia
Pelger-Huet anomaly
primary biliary cholangitis

Mouse Phenotypes
abnormal granulocyte differentiation
abnormal neutrophil differentiation
decreased T cell proliferation
thymus hypoplasia
enlarged spleen
abnormal blood cell morphology/development
abnormal eosinophil morphology
decreased mean corpuscular hemoglobin
abnormal granulocyte morphology
increased neutrophil cell number
abnormal neutrophil morphology
abnormal lymphocyte cell number
decreased B cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased T cell number
decreased lymphocyte cell number
increased monocyte cell number
decreased leukocyte cell number
abnormal lymphocyte morphology
abnormal spleen morphology
spleen hypoplasia
abnormal B cell physiology
abnormal T cell physiology
Availability Mouse Genotype
Lbrem1(IMPC)Tcp/Lbrem1(IMPC)Tcp
LbrGt(XE569)Byg/LbrGt(XE569)Byg
Lbric-2J/Lbric-2J
Lbric-3J/Lbric-3J
Lbric-J/Lbric-J
Lbrlym3/Lbrlym3
Lbric-J/Lbr+
Lbric-J/Lbrlym3
Lbrlym3/Lbr+
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory